HA cosmetics only act on the surface layer of the skin at the application site, increasing the HA content on the surface of the skin, acting as a moisturizing and moisturizing effect, and is local. The oral HA beauty care product is a systemic effect, which increases the content of endogenous HA from the dermis to the epidermis, activates the cells, exerts a systemic effect, and is significantly different from the topical use of cosmetics. Surface beauty mainly considers the care of the local epidermis, but has no effect on the dermis which is a major component of the skin. The dermal matrix is mainly composed of collagen and HA and other mucopolysaccharides. As the age increases, the aging of the skin is caused by the change of collagen, and the change of collagen is caused by the decrease of HA with water retention. Therefore, to maintain the function of collagen, it is necessary to supplement HA.